Fig. 5: Absolute and relative contribution to HIV reservoirs by cell proliferation, death, and differentiation. | Nature Communications

Fig. 5: Absolute and relative contribution to HIV reservoirs by cell proliferation, death, and differentiation.

From: Estimating the contribution of CD4 T cell subset proliferation and differentiation to HIV persistence

Fig. 5

A–D Absolute contributions to HIV subset DNA by differentiation in, proliferation, differentiation out, and death of each subset. E Relative contribution of each mechanism to each subset. Positive (persistence) and negative (clearance) contributions are treated separately for % calculations. Differentiation out and death of TEM are grouped together because the lack of terminally differentiated cells in this analysis precluded identification of both rates. In A–E, estimate for each individual (N = 24) are shown as colored dots and black diamonds indicate means across individuals. F The absolute contribution of each mechanism averaged across all individuals.

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