Table 1 Fixed effect formulas used for each MEM model and their corresponding figures or data file

From: Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures

Fixed effects

Figures

IDH_mutation

Fig. 2c, d, Supplementary Fig. 3a–e

EGFR_cnv+EGFR_mut+CDKN2A_cnv+NF1_cnv+NF1_mut+TP53_cnv+TP53_mut+PTEN_cnv+PTEN_mut

Supplementary Fig. 5a

EGFR_cnv

Supplementary Fig. 5b, c

NF1_cnv*EGFR_cnv

Supplementary data 2

CDKN2A_cnv*EGFR_cnv

Fig. 5c, d, Supplementary Fig. 5d, e

TP53_cnv*EGFR_cnv

Supplementary data 2

Pathway-based classification

Supplementary data 2

  1. * denotes both terms as single effects and an interacting term (ex. IDH_mut*EGFR_cnv= IDH_mut+ EGFR_cnv + IDH_mut:EGFR_cnv. “Mut” indicates mutation status (mutated versus wild type) and “cnv” indicates copy number variation.
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