Fig. 2: Heatmap for associations of the 70 HFpEF-related eicosanoid and eicosanoid-related metabolites with exercise traits in the MGH CPET sample.

Color coding represents standardized ß-coefficient in primary model (X-SD change in exercise trait per 1-SD change in eicosanoid metabolite). Primary analyses are adjusted for age, sex, and plate number. Clustering is based on exercise traits (columns). Color scale indicates positive associations in red, and negative associations in blue. CO cardiac output, HR heart rate, PAP pulmonary artery pressure, PCWP pulmonary capillary wedge pressure, SBP systolic blood pressure. Source data are provided as a Source Data file.