Fig. 3: Preliminary results and control experiments. | Nature Communications

Fig. 3: Preliminary results and control experiments.

From: Regio- and enantioselective synthesis of acyclic quaternary carbons via organocatalytic addition of organoborates to (Z)-Enediketones

Fig. 3

A Nearly no reactivity was observed with the trans diketone. B The cis substrate afforded catalytic activity that produced the acyclic quaternary carbon product in high yield and with high stereoselectivity despite a significant background reaction also being operative. C Pure trans diketone or a mixture of cis and trans could be converted to cis-enriched substrate that then reacted in a similar manner to pure cis diketone. 4Å-MS 4Å molecular sieves, PhMe toluene, er enantiomeric ratio, CFL Compact Fluorescent Lightbulb.

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