Fig. 2: Baseline viral load and spike antibody relationships with each other, CRP, demographics and co-morbidities. | Nature Communications

Fig. 2: Baseline viral load and spike antibody relationships with each other, CRP, demographics and co-morbidities.

From: Randomized controlled trial of molnupiravir SARS-CoV-2 viral and antibody response in at-risk adult outpatients

Fig. 2

a Baseline viral load increase with age. b Baseline viral load decrease with time since symptom onset. c Baseline viral load decrease with increased baseline spike antibody (S-Ab). d Baseline viral load increase with increase in CRP measured in capillary blood. e Geometric mean viral load ±95%CI with time compared with a t test showing baseline viral load higher in males and in patients with kidney disease. f Geometric mean S-Ab ±95%CI with time compared with a t test showing baseline S-Ab lower in males and participants who were not fully vaccinated. LLOQ is lower limit of quantification which for viral load was 109 cp/mL. For (a–d) the slope was compared with zero using the f statistic, for figures (e) and (f) and t test was used to compare geometric mean values. *P < 0.05, **P < 0.01, ***P < 0.001. Source data are provided as a Source Data file.

Back to article page