Fig. 1: Chemical structures of HA derivatives. | Nature Communications

Fig. 1: Chemical structures of HA derivatives.

From: Inhibition of urease-mediated ammonia production by 2-octynohydroxamic acid in hepatic encephalopathy

Fig. 1

a Structures of saturated aliphatic HAs with the varying lengths of the alkyl chain that were either synthesized (heptanohydroxamic acid (HHA), nonanohydroxamic acid (NHA), decanohydroxamic acid (DHA), laurohydroxamic acid (LHA)) or purchased (acetohydroxamic acid (AHA), octanohydroxamic acid (OHA)). b Structures of unsaturated derivatives of OHA (trans-2-octenohydroxamic acid (2-octenoHA), trans-3-octenohydroxamic acid (3-octenoHA), 2-octynohydroxamic acid (2-octynoHA), 3-octynohydroxamic acid (3-octynoHA), 7-octynohydroxamic acid (7-octynoHA)). The structure of the lead inhibitor is shown in red.

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