Fig. 2: Substituent effect of benzyl bromide substrate 2.

Reaction conditions: 1a (0.2 mmol), 2 (0.24 mmol), Pd₂(dba)₃ (5 mol%), L7 (10 mol%), LiO^tBu (3.0 equiv.), dioxane (2.0 mL) in a sealed vial at 50 °C for 36 h. ^aWith L9 (10 mol%) as the ligand.