Fig. 6: Electrical activity recording.
From: Three-dimensional liquid metal-based neuro-interfaces for human hippocampal organoids
a (Upper) Raster plots of neural spikes, and (lower) the continuous signal in a channel of the mMPC. b Continuous recording for a spike. c The uniform spike waveforms and the average waveform in a channel of the mMPC. d Two different spikes appeared in the same channel (upper) and the sorting results (lower). e The comparison of spike rates detected by the mMPC and the 2D MEA (these channels covered by the hHO). f The synchronous signals between two channels. (Upper) Raster plots of neural spikes in these two channels and (lower) continuous recording for two spikes. The time interval was <1 ms. g The oscillatory network activity of the hHO. (Upper) the population activity histogram and (lower) the raster plot (black) identified bursts of spiking detected on 32 channels and coordinated bursts (red) of activity across channels. h Raster plots before and after Glutamine supplement. i 3D visualization plot showing average spike numbers throughout 128 channels. mMPC mesh liquid metal-polymer conductor, MEA multi-electrode array.
