Fig. 3: Differential abundance diversity and trial arm. | Nature Communications

Fig. 3: Differential abundance diversity and trial arm.

From: Effects of iron supplements and iron-containing micronutrient powders on the gut microbiome in Bangladeshi infants: a randomized controlled trial

Fig. 3

Volcano plots presenting differential abundance by trial arm immediately post-intervention, with (A) showing no significant differences at the species level and (B) showing no significant differences in abundance of functional pathways measured by HUMAnN 3.0 (Shotgun metagenomic data). Relative abundance data underwent centered log ratio normalization/transformation in a general linear model analysis in MaAsLin2, with data for differentially abundant species and functional pathways including coefficient (approximating log2-fold change), standard deviation and FDR-adjusted p value. Each figure shows log2-fold change on the x-axis and the −log10(FDR-adjusted p value) on the y-axis. The horizontal red line indicates an FDR-adjusted p value 0.05. Source data for this figure are provided in the Source Data file.

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