Fig. 2: Overview of cetuximab response and biomarker candidates. | Nature Communications

Fig. 2: Overview of cetuximab response and biomarker candidates.

From: Integrative ensemble modelling of cetuximab sensitivity in colorectal cancer patient-derived xenografts

Fig. 2

a Mutation patterns of CRC driver genes and mutational signature features among those with the most significant impact on CeSta predictions (Fig. 4a) b cetuximab non-responders (‘PD’, volume growth > 35%, in orange) and responders (‘SD-OR’, volume growth ≤35%, in blue). c Selection of continuous features which best differentiate between PD and SD-OR PDX models. Source data are provided as a Source Data file.

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