Fig. 8: The therapeutic efficacy of microorganism micro-engine microneedles (MM-MNs) for chronic psoriasis treatment. | Nature Communications

Fig. 8: The therapeutic efficacy of microorganism micro-engine microneedles (MM-MNs) for chronic psoriasis treatment.

From: Microorganism microneedle micro-engine depth drug delivery

Fig. 8

a Establishment of the animal model and treatment procedure. Created with BioRender.com/u33l993. b Changes in PASI scores during the treatment process. Mean ± SD of n = 3 independent samples. c H&E staining results of the back skin in each group. Scale bar, 300 μm. d Changes in the condition of the back of mice during the treatment process. e–j ELISA experiment to measure the levels of psoriasis-related inflammatory factors. (e): IL-17A; (f): IL-17F; (g): IL-10; (h): IL-22; (i): IL-23; (j): CXCL1; e–j mean ± SD of n = 3 independent samples. Two-sided Student’s t test. A representative image of three biologically independent samples from each group is shown in (c) and (d).

Back to article page