Fig. 2: The development of spatial coding properties with age.
From: Early and late place cells during postnatal development of the hippocampus
a Example spatial rate maps of CA1 cells in the 2D navigation task at various ages. The spatial information (SI) score of each cell was labeled above its rate map. b The SI scores of all active cells at different ages in the 2D navigation task. Dots with bars indicate the mean values and the 95% confidence intervals. The SI significantly increased with development (Pearson correlation coefficient r = 0.32, p < 10–15, n = 28570 cells), but showed no changes across recording days in adults (r = 0.004, p = 0.67, n = 12100 cells). c Example spatial rate maps of CA1 cells for two running directions (red and brown) in the 1D shuttling task over various postnatal days. The number on top, the mean SI score from the two directions. The shaded region indicates SD. d Same as (b), but for the 1D shuttling task. The mean SI score for the two directions was used for a given cell. There was a significant increase in SI with development (r = 0.34, p < 10–15, n = 34857 cells), but no changes across recording days in adults (r = − 0.006, p = 0.65, n = 5620 cells). Source data are provided as a Source Data file.
