Fig. 3: Comparison of mutated residues of the mutant HheD8-M3 with the wild type HheD8-WT/AF.
From: Biocatalytic enantioselective formation and ring-opening of oxetanes
a Close-up view of the A69F mutation in the active site. b Close-up view of the M124P and R127G mutations in the active site. HheD8-M3 (PDB code: 8XXB) is shown as blue cartoon. HheD8-WT (AFDB code: AF-N6YXW4-F1) is shown as gray cartoon. Catalytic triad S117-Y130-R134, the mutated residues (A69F, M124P, and R127G), and (R)−1b are highlighted in sticks. The ligand Cl− is highlighted in green sphere.
