Fig. 3: Heterochromatin is accessible but methylated at a slower rate than euchromatin.
From: Nucleosome dynamics render heterochromatin accessible in living human cells
a Methylation time courses and methylation rates for the median GATC site in regions with active histone marks (H3K4me1, H3K4me3, H3K27ac, H3K36me3) and inactive histone marks (H3K9me3 and H3K27me3). b ChromHMM model defining 15 epigenetic states in MCF7 cells, defined as active or inactive chromatin based on the histone marks. c Methylation time courses and methylation rates for the median GATC site in the active chromatin (euchromatin) states defined by the HMM model. d Methylation time courses and methylation rates for the median GATC site in the inactive chromatin (heterochromatin) states defined by the HMM model.
