Extended Data Fig. 2: Target gene silencing by histone H3K27me3 deposition.
From: A gene silencing screen uncovers diverse tools for targeted gene repression in Arabidopsis
a, Screenshots of H3K27me3 and H3 ChIP–seq signals over a representative ZF off-target site in fwa and T2 transgenic lines of LHP1-ZF, MSI1-ZF and ELF7-ZF. b, Screenshots of H3K27me3, H3K4me3, Pol II Ser5 and H3 ChIP–seq signals in fwa and T2 transgenic lines of EYFP-ZF at the FWA region. The FLAG-ZF ChIP–seq signals indicate ZF binding sites. c, Heat maps and metaplots showing the normalized H3K27me3, H3K4me3, Pol II Ser5 ChIP–seq signals over ZF off-target sites and shuffled sites (n = 6,091) in the EYFP-ZF T2 transgenic line versus fwa.
