Table 2 The levles of initial glycans from NC, MCI, and dementia patients.

From: Association of dementia with immunoglobulin G N-glycans in a Chinese Han Population

GPs

NC (n = 81)

MCI (n = 108)

Dementia (n = 81)

p*

Median (P25–P75)

Median (P25–P75)

Median (P25–P75)

GP1

0.05 (0.02–0.20)

0.37 (0.16–0.60)

0.33 (0.22–0.57)#$

<0.001

GP2

0.28 (0.10–0.45)

0.37 (0.17–0.73)

0.45 (0.24–0.78)#$

0.001

GP4

42.02 (34.75–47.92)

41.59 (34.85–47.32)

39.16 (34.28–45.70)a

0.575

GP5

0.00 (0.00–0.02)

0.05 (0.01–0.17)

0.20 (0.07–0.36)#&$

<0.001

GP6

6.22 (4.76–7.78)

6.23 (5.17–7.52)

6.51 (5.21–7.73)a

0.937

GP7

0.01 (0.00–0.05)

0.14 (0.05–0.27)

0.15 (0.05–0.40)#$

<0.001

GP8

11.53 (10.35–12.87)

12.35 (10.02–13.91)

14.46 (13.11–15.57)#&

<0.001

GP9

2.97 (1.72–4.64)

3.35 (2.00–5.06)

4.29 (3.29–5.58)#&

<0.001

GP10

0.73 (0.52–1.13)

1.11 (0.57–1.93)

2.12 (1.19–2.87)#&$

<0.001

GP11

0.08 (0.06–0.23)

0.31 (0.14–0.60)

0.10 (0.05–0.31)&$

<0.001

GP12

0.14 (0.04–0.32)

0.16 (0.08–0.31)

0.32 (0.17–0.58)#&

<0.001

GP13

0.14 (0.04–0.32)

0.31 (0.15–0.76)

0.36 (0.25–0.73)#$

<0.001

GP14

13.73 (11.43–17.54)

13.02 (8.74–16.56)

11.24 (7.89–14.26)a#

0.001

GP15

0.11 (0.06–0.18)

0.21 (0.11–0.43)

0.45 (0.23–0.68)#&$

<0.001

GP16

3.97 (2.96–4.64)

3.66 (2.99–4.49)

2.93 (2.34–3.46)a#&

<0.001

GP17

0.83 (0.51–1.20)

0.56 (0.34–0.90)

0.75 (0.57–1.12)&$

<0.001

GP18

10.52 (7.73–13.29)

9.27 (7.75–12.12)

7.2 (5.89–9.06)#&

<0.001

GP19

1.76 (1.28–2.24)

1.86 (1.31–2.42)

1.77 (1.29–2.12)

0.429

GP21

0.23 (0.17–0.31)

0.18 (0.13–0.26)

0.32 (0.23–0.53)#&$

<0.001

GP22

0.07 (0.46–0.14)

0.14 (0.07–0.27)

0.11 (0.08–0.24)#$

<0.001

GP23

0.67 (0.42–1.03)

0.53 (0.34–0.82)

0.84 (0.50–1.10)&$

<0.001

GP24

0.82 (0.59–1.33)

0.83 (0.49–1.21)

0.76 (0.47–1.05)

0.449

  1. NC normal cognitive functioning, MCI mild cognitive impairment.
  2. *p < 0.05 was considered statistically significant.
  3. #p < 0.017, Dementia group compared with NC group.
  4. $p < 0.017, MCI group compared with NC group.
  5. &p < 0.017, Dementia group compared with MCI group.
  6. aAnalysis of variance (ANOVA).