Fig. 6: ΔsaeRS strain-induced activation of the NF-κB pathway in macrophages is dependent on the TLR2 receptor. | npj Biofilms and Microbiomes

Fig. 6: ΔsaeRS strain-induced activation of the NF-κB pathway in macrophages is dependent on the TLR2 receptor.

From: Staphylococcus aureus SaeRS impairs macrophage immune functions through bacterial clumps formation in the early stage of infection

Fig. 6

A, B Western blot analysis of p65 phosphorylation levels. C Representative images of p65 nuclear translocation in different treatment groups (Scale bar, 5 μm). D Gene expression and product concentrations of inflammatory and chemotactic factors in THP-1 cells after different treatments. E Representative images of THP-1 macrophages engulfing S. aureus (Scale bar, 10 μm). F The phagocytosis rates of THP-1 cells. n = 3 per group. * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001. Data are presented as means ± SD.

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