Fig. 9: saeRS mutation affects in vivo infection-related immune processes. | npj Biofilms and Microbiomes

Fig. 9: saeRS mutation affects in vivo infection-related immune processes.

From: Staphylococcus aureus SaeRS impairs macrophage immune functions through bacterial clumps formation in the early stage of infection

Fig. 9

A Representative immunohistochemical images of F4/80 within the peri-implant infected soft tissues for each group on days 4 and 14 after surgery (Scale bar, 50 μm). B Representative immunohistochemical images of Ly6G in the tissues surrounding the implants on days 4 and 14 after surgery (scale bar, 50 μm). C Representative immunofluorescence staining images of CD11b and MPO in the tissues surrounding the implants for each group on days 4 and 14 after surgery (Scale bar, 50 μm). D Representative immunofluorescence staining images of iNOS and CD206 in the tissues surrounding the implants on days 4 and 14 after surgery (Scale bar, 50 μm). E Representative ROS fluorescence staining images and the corresponding fluorescence intensity of the peri-implant soft tissues on days 4 and 14 after surgery (Scale bar, 50 μm). F–H Corresponding relative fluorescence intensities of CD11b (F), iNOS (G), and CD206 (H) in the tissues surrounding the implants at 4 and 14 days after surgery. I–K Contents of CXCL2 (I), TNF-α (J), and IL-1β (K) in the soft tissues surrounding the implants on days 4 and 14 after surgery. L Corresponding relative fluorescence intensity of ROS in soft tissues. n = 3 per group. * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001. Data are presented as means ± SD.

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