Fig. 4: In vivo efficacy study of pevonedistat.
From: Targeting neddylation and sumoylation in chemoresistant triple negative breast cancer
Tumor volume growth curves for individual PDX models treated either with vehicle (black) or pevonedistat (red). Statistical significance denoted under the PDX_ID, was determined using a two-way ANOVA applied to the time series. Arrows connect paired models, with pre-NACT models on the left and corresponding mid/post-NACT models on the right. Data points and error bars show the mean and standard deviation respectively.
