Fig. 4: Effects of constitutive loss of FoxO3 on hepatocyte ploidy during liver regeneration in adult mice.
From: FoxO3 restricts liver regeneration by suppressing the proliferation of hepatocytes
Primary hepatocytes isolated from livers at 2 (a, b), 4 (c, d), and 7 (e, f) dpH were subjected to ploidy contribution analysis using flow cytometry. Representative images (a, c, and e) and quantification (b, d, and f) of the ploidy contribution of hepatocytes isolated from Con and AKO mice are shown (n = 3 mice per group). Peaks 1, 2 and 3 depicted, respectively, 2 C, 4 C, and 8 C cells. All data are presented as the mean ± SEM. **p < 0.01 versus control mice (two-way ANOVA test).
