Fig. 3: Effect of miR-10a delivered by QDP in modulating macrophage polarity by suppressing LPS-induced NF-ÎşB, MAPK, and AKT signaling pathways. | npj Regenerative Medicine

Fig. 3: Effect of miR-10a delivered by QDP in modulating macrophage polarity by suppressing LPS-induced NF-ÎşB, MAPK, and AKT signaling pathways.

From: Quantum dots as biocompatible small RNA nanocarriers modulating macrophage polarization to treat Asherman’s syndrome

Fig. 3

A The relative mRNA levels of M1 (iNos, Socs3) and M2 (Arg1, Mrc1) markers were analyzed by real-time RT-PCR in the RAW264.7 cells. Statistical analyses were performed using a t-test *p < 0.05 vs. LPS, **p < 0.01 vs. LPS, #p < 0.05 vs. Naïve. B Western blotting analyses for the effects of QDP/miR-10a for the suppression of NF-κB, MAPK, and AKT signaling pathways that were induced activation by LPS in the RAW264.7 cells. α-Tubulin was used as a loading control.

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