Table 1 Demographic characteristics and clinical of SCZ and MUD-MIP before treatment.

From: Psychotic symptoms associated increased CpG methylation of metabotropic glutamate receptor 8 gene in Chinese Han males with schizophrenia and methamphetamine induced psychotic disorder: a longitudinal study

 

SCZ (n = 109)

MUD-MIP (n = 99)

t/χ2

p

Mean ± SD (%)

Mean ± SD (%)

Age

26.46 ± 6.598

31.52 ± 6.211

−5.676

<0.001

Marital status

  

21.271

<0.001

Unmarried

41 (37.61%)

63 (63.63%)

  

Married or cohabiting

63 (57.79%)

26 (26.39%)

  

Divorced or widowed

5 (4.58%)

10 (10.10%)

  

Education

  

5.723

0.057

Junior high school and below

45 (41.28%)

51 (51.52%)

  

Vocational or high school

40 (36.70%)

38 (38.38%)

  

College degree, undergraduate degree, or above

24 (22.02%)

10 (10.10%)

  

First-episode psychosis

60 (55.04%)

48 (48.48%)

0.895

0.405

PANSS total

109.02 ± 14.13

106.39 ± 9.66

1.548

0.123

PANSS positive

28.39 ± 4.73

29.91 ± 4.06

−2.500

0.113

PANSS negative

25.24 ± 6.13

21.83 ± 4.66

4.542

<0.001

PANSS general psychopathology

55.39 ± 7.77

54.66 ± 5.59

0.779

0.437

WHODAS 2.0 total scores

112.40 ± 9.16

110.94 ± 8.93

1.161

0.247

WHODAS2.0 functioning domains

Cognition

18.68 ± 1.72

17.88 ± 2.61

2.631

0.009

Getting around

12.97 ± 1.93

12.65 ± 2.28

1.280

0.266

Self-care

13.45 ± 1.57

13.72 ± 1.46

−1.267

0.207

Self-care

17.39 ± 2.08

17.79 ± 2.11

−1.354

0.177

Life activities

Household

13.59 ± 2.13

13.65 ± 2.13

−0.201

0.841

Work

13.76 ± 1.73

13.65 ± 1.70

0.484

0.629

Participation

22.56 ± 4.82

21.62 ± 5.04

1.373

0.171

WHODAS 2.0 classification

  

1.409

0.703

I (≥116)

43 (39.44%)

30 (30.30%)

  

II (106–115)

36 (33.03%)

35 (35.35%)

  

III (96–105)

28 (25.69%)

24 (24.24%)

  

IV (52–95)

2 (1.83%)

3 (3.03%)

  

CGI (SI)

6.24 ± 0.67

6.16 ± 0.67

0.833

0.406

  1. SD standard deviation, PANSS Positive and Negative Syndrome Scale, WHODAS 2.0 World Health Organization Disability Assessment Schedule II, CGI Clinical Global Impression Scale, SCZ schizophrenia, MUD methamphetamine use disorder, MIP methamphetamine-induced psychotic disorder.