Fig. 2: Breadth of the cross-neutralization response against sarbecovirus is associated with the potency of the antibody response.

A The neutralization breadths of convalescent (left panel) and vaccinee (right panel) plasma samples against eight sarbecoviruses are defined by the range of breadth from 0 to 8. B Correlations between neutralization breadths and neutralization titers against sarbecoviruses in convalescents (left) and vaccinees (right). Spearman’s rank correlation coefficient was employed to assess the association between the neutralization breadth and neutralization titers. P < 0.05 was considered statistically significant using a two-tailed test.