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Mechanopathology

Activating membrane receptors with ultrasound

Nature Biomedical Engineering volume 9, pages 601–603 (2025)Cite this article

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Non-invasive ultrasonic activation of RET increases colonic cell proliferation primarily through acoustic pressure.

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Fig. 1: Ultrasound stimulation activates RET in colonic crypt cells through acoustic pressure achieved by modulating pulse parameters.

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Acknowledgements

This work was partially supported by the National Science Foundation number 2327144 and NIH R01 AR61821.

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  1. Department of Biomedical Engineering, State University of New York - Stony Brook University, Stony Brook, NY, USA

    Yi-Xian Qin & Elias Georgas

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  1. Yi-Xian Qin
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  2. Elias Georgas
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Correspondence to Yi-Xian Qin.

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The authors declare no competing interests.

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Qin, YX., Georgas, E. Activating membrane receptors with ultrasound. Nat. Biomed. Eng 9, 601–603 (2025). https://doi.org/10.1038/s41551-025-01395-8

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