Extended Data Fig. 6: qPCR and western blots of LF samples by disease group. | Nature Biomedical Engineering

Extended Data Fig. 6: qPCR and western blots of LF samples by disease group.

From: ROCK-dependent mechanotransduction of macroscale forces drives fibrosis in degenerative spinal disease

Extended Data Fig. 6

A, while overall qPCR analysis of LF from non-DSD, DSD, and ASD patients was highly variable, Fibronectin increased stepwise between non-DSD, DSD, and ASD groups. CYP also significantly decreased from non-DSD levels. B, As quantified by western blots on LF samples, similar levels of latent TGFβ were present in all disease groups but the amount of released, active TGFβ was highest in non-DSD samples and lowest in ASD samples. Quantitative data are shown as mean ± sem.

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