Extended Data Fig. 8: Tmem63 mutant flies are vulnerable to starvation.
From: Drosophila TMEM63 and mouse TMEM63A are lysosomal mechanosensory ion channels
a, Schematic showing the starvation stress treatment starting from the third-stage larvae (L3). b, Percentage of viable larvae for wild type (WT), Tmem63 mutants, and Tmem63 mutants re-expressing the Tmem63 gene (Tmem63 rescue). c, Climbing activities of young adult flies at day 4. All data shown are mean ± s.e.m. Statistical significance was determined by two-sided Student’s t-test (b, c). The numbers of animals are shown beneath the bars. The fly genotypes in b and c are indicated in Supplementary Table 1. Numerical data are available as source data.
