Extended Data Fig. 1: Persistent RSL3 or erastin induces membrane PL saturation.
From: LPCAT1-mediated membrane phospholipid remodelling promotes ferroptosis evasion and tumour growth
a, Viability analysis of the indicated cells treated with RSL3 or erastin. b–e, Relative cellular levels of GSH (b, d), DCFH-DA (c), and Ferro-Orange (e) were examined in the indicated RSL3- or erastin-treated cells. f, IB analysis of GPX4, FSP1, GCH1, DHODH, LPCAT3 and ACSL4 expression in the indicated cells. GAPDH served as a loading control. Data are presented as mean ± SD, n = 3 biologically independent samples in a, f, n = 6 biologically independent samples in b-e. Statistical analysis was performed using one-way ANOVA followed by Dunnett’s test in b-e, two-way ANOVA followed by Tukey’s test in a. NS, not significant.
