Extended Data Fig. 8: The activity of Nr5a2 in zebrafish intestinal cells.
From: A single-cell atlas of chromatin accessibility in mouse organogenesis
a-b, t-SNE projection of cells at 24 hours post fertilization (hpf; a) and 72 hpf (b) in zebrafish, colored by cell type annotation. LLP, Lateral line primordium; DN, Differentiating neurons; RPE, Retina pigmented epithelium; FP, Floor plate; Dien, Diencephalon; Telen, Telencephalon; P. arch, Pharyngeal arch; Epi, Epidermal; YSL, yolk syncytial layer; LP, Lateral plate. c, t-SNE projection of cells at 24 hpf (a) and 72 hpf (b) in zebrafish, colored by the gene activity scores or the motif activity score of Nr5a2. The cells in the green circles were zebrafish intestinal cells. d, DNA binding-site motif of mouse Nr5a2 from the CIS-BP database27 (left) and zebrafish nr5a2 from Baranasic, et al.58.
