Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Biophysical chemistry

How membranes influence intracellular phase separation

Nature Chemistry volume 16, pages 10–11 (2024)Cite this article

Subjects

Liquid–liquid phase separation (LLPS) within cells is a captivating phenomenon known to aid the organization of cellular components; however, its complex kinetics have remained a puzzle. Now, a new study elucidates the crosstalk between the phase state of an encapsulating membrane and LLPS dynamics.

Access through your institution
Buy or subscribe

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Access through your institution

Buy this article

  • Purchase on SpringerLink
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Response of vesicles loaded with PEG and dextran when exposed to osmotic deflation.

References

  1. Jones, R. A. L., Norton, L. J., Kramer, E. J., Bates, F. S. & Wiltzius, P. Phys. Rev. Lett. 66, 1326–1329 (1991).

    Article  CAS  PubMed  Google Scholar 

  2. Crowe, C. D. & Keating, C. D. Interface Focus 8, 20180032 (2018).

    Article  PubMed  PubMed Central  Google Scholar 

  3. Dimova, R. & Lipowsky, R. Adv. Mater. Interfaces 4, 1600451 (2017).

    Article  Google Scholar 

  4. Su, W.-C. et al. Nat. Chem. https://doi.org/10.1038/s41557-023-01267-1 (2023).

    Article  PubMed  Google Scholar 

  5. Alberti, S., Gladfelter, A. & Mittag, T. Cell 176, 419–434 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Babl, L., Merino-Salomón, A., Kanwa, N. & Schwille, P. Sci. Rep. 12, 17949 (2022).

    Article  CAS  PubMed Central  Google Scholar 

  7. Mangiarotti, A., Chen, N., Zhao, Z., Lipowsky, R. & Dimova, R. Nat. Commun. 14, 2809 (2023).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Mangiarotti, A. et al. Nat. Commun. 14, 6081 (2023).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Wang, H.-Y. et al. Sci. Adv. 9, eadf6205 (2023).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Max Planck Institute of Colloids and Interfaces, Science Park Golm, Potsdam, Germany

    Rumiana Dimova

Authors
  1. Rumiana Dimova
    View author publications

    Search author on:PubMed Google Scholar

Corresponding author

Correspondence to Rumiana Dimova.

Ethics declarations

Competing interests

The author declares no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Dimova, R. How membranes influence intracellular phase separation. Nat. Chem. 16, 10–11 (2024). https://doi.org/10.1038/s41557-023-01407-7

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41557-023-01407-7

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing