Extended Data Fig. 5: G4 binding of trans-9 in the promoters of several of its most significantly downregulated genes.
From: Optical control of gene expression using a DNA G-quadruplex targeting reversible photoswitch
Genome browser views display trans-9 Chem-map binding sites (red), overlapping with naturally occurring G4 sites mapped by G4-CUT&Tag (blue), at the promoter regions of several genes that are most significantly downregulated by trans-9 (fold change >2, q ≤ 0.05, p < 10-8), as randomly selected from those highlighted in Extended Data Fig. 4c.
