Extended Data Fig. 2: Effects of nuclear stiffness on the nuclear jamming transition.
From: A nuclear jamming transition in vertebrate organogenesis
Dependence of the long timescale MSRD values (top) and neighbor exchange rate (bottom) for large nuclear volume fraction (\({\phi }_{N}=0.85\)) on the ratio of nuclear stiffness \({E}_{N}\) and the characteristic stress scale of cell deformations \({T}_{0}/{L}_{0}\). Large (small) values of \({E}_{N}/({T}_{0}/{L}_{0})\) indicate hard (soft) nuclei compared to the cell. Red lines are the values of long time MSRD and neighbor exchange rate for zero nuclear volume fraction (\({\phi }_{N}=0\)), and the vertical cyan dashed line indicates the point at which nuclear stiffness and the stress scale of cell deformations are equal, namely \({E}_{N}={T}_{0}/{L}_{0}\). Error bands indicate standard deviation over N = 10 simulations.
