Extended Data Fig. 4: Evaluation of pro-inflammatory cytokine profiles in proximal murine colons.
a-j, Concentration (pg/mg) of cytokines IFN-γ (a), IL-10 (b), IL-12p70 (c), IL-17 (d), IL-1β (e), IL-22 (f), IL-4 (g), IL-6 (h), KC/GRO (i) and TNF-α (j) respectively, in murine proximal colonic samples, stratified into groups: Control (n = 5), ABX (n = 5), pfoA+ (n = 15), pfoA- (n = 15). All individual samples were measured in technical duplicates (n = 2). The box in boxplot represents 50% of the central data, in between lower and upper quartile, with a central line representing the median while whiskers show the most extreme data points. All statistical analyses were performed with Kruskal-Wallis test and post-hoc Dunn’s test of multiple comparisons with P values adjusted by Benjamini-Hochberg method, unless otherwise stated. Significance was tested against untreated group, otherwise significance brackets will be used in pairwise comparison.
