Extended Data Fig. 1: Waterfall plot of maximum change in tumour size by RECIST after treatment with cobimetinib in patients with histiocytosis.
From: Efficacy of MEK inhibition in patients with histiocytic neoplasms
The upper and lower dotted lines represent cut-offs for progressive disease and partial response, respectively. Colours of bars indicate the genomic alteration present. Notations above bars indicate the specific mutation. One patient (marked by an asterisk) had undergone previous BRAF inhibitor therapy that was discontinued owning to intolerance. One patient (marked by a dagger) died owing to underlying disease. n = 14 patients in total.
