Extended Data Fig. 10: Stimulation of spinally projecting excitatory latRM neurons recruits forelimb muscles in a sequence resembling natural reaching.
From: A functional map for diverse forelimb actions within brainstem circuitry
a, Scheme depicting implantation of EMGs into forelimb biceps and triceps muscles, and raw signal demonstrating that these muscles are active in alternation during natural locomotion (below), according to their flexor (biceps) and extensor (triceps) function. b, EMG recordings and quantification (latency and relative onset) for biceps and triceps recordings during optogenetically induced reaching by stimulation of spinally projecting excitatory latRM neurons (top; n = 3 mice for biceps and triceps) or natural reaching (bottom; 0 = reaching onset; n = 3 mice for biceps and n = 2 mice for triceps). Grey shades, ±s.e.m.; *P < 0.05; **P < 0.01; two-sided paired t-test.
