Extended Data Fig. 10: MicroCT of the lung of infected hamsters.
From: Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation
a, MicroCT axial and coronal images of the lungs of Syrian hamsters at 7 d.p.i. with D614G-infected (n = 4), D614G/P681R-infected (n = 4), and uninfected hamsters (n = 3). Lung abnormalities included multifocal nodules (black arrows), ground glass opacity (white arrowheads), and regions of lung consolidation (white arrows) that were peripheral, bilateral, and multilobar. Pneumomediastinum is labelled with white asterisks. b, Summary of CT severity score. CT severity score of D614G-infected (n = 4), D614G/P681R-infected (n = 4), and uninfected hamsters (n = 3) Syrian hamsters. Each dot indicates the result of the respective infected hamster. Note that D614G/P681R-infected animals had a higher average CT severity score compared to D614G-infected animals.
