Extended Data Fig. 4: Variants called in additional mutation accumulation datasets. | Nature

Extended Data Fig. 4: Variants called in additional mutation accumulation datasets.

From: Mutation bias reflects natural selection in Arabidopsis thaliana

Extended Data Fig. 4

a, Germline and somatic mutations around gene regions in mutation accumulation lines derived from eight founder genotypes. For each founder, 35-60 lines were propagated for 8-10 generations. b, The proportion of somatic variants detected in gene bodies (gene body/(gene body + upstream + downstream)) among descendants of the same founder. F- and p-values from one-way ANOVA. (n = 400 unique mutation accumulation lines, mean ± 2 s.e.m.) c, Somatic variants detected from reanalysis of 64 individual leaves from two Col-0 plants21. d, Germline variants detected in a bottlenecked A. thaliana lineage following colonization of North America since ~1600 (ref. 32). e, Epigenome-predicted and observed mutation rates across all datasets for InDels and SNVs, comparing gene bodies (GB) with upstream/downstream (U/D) regions. P-values from chi-squared tests.

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