Extended Data Fig. 9: Influence of sample size on the robustness of brain-wide associations.
From: Reproducible brain-wide association studies require thousands of individuals
Trajectories of sampling variability (99% confidence interval; orange), statistical error rates (cumulative sum of false negatives, false positives, magnitude errors, sign errors; yellow), and support vector regression (SVR) out-of-sample association strength (as % of full in-sample association; dark red) as a function of sample size. Sample size (n ~ 4,000) represents a full sample (discovery + replication datasets of ~2,000 each). Data shown are from ABCD Study.
