Extended Data Fig. 3: Reanalyzing the scRNA data from substantia nigra.
From: Reply to: Ptbp1 deletion does not induce astrocyte-to-neuron conversion
a, UMAP of cells from substantia nigra of different genotypes. b, Relative quantity of cells in different clusters (indicated at top). c, Expression of GFP, Ptbp1, and Ptbp2 in individual cell clusters from WT (red), heterozygous (green), and homozygous (blue) Ptbp1 KO mice. d, Expression of top 10 marker genes in Cluster 5, compared with other clusters (right). Green text: astrocytic genes, Red text: neuronal genes. e, Identification of potential doublets with DoubletFinder, showing that most cells in Cluster 5 are unlikely to be doublets.
