Fig. 4: Neurological improvements following neurorehabilitation supported by the BSI in the absence of stimulation.
From: Walking naturally after spinal cord injury using a brain–spine interface

a, Chronophotography illustrating the walking ability of the participant without any stimulation before enroling in the STIMO clinical trial (pre-STIMO), after its completion (post-STIMO) and after completion of the STIMO-BSI clinical trial (post-BSI). b, Timeline of the two clinical trials, including a pie chart reporting the time during which the various types of neurorehabilitation exercises were practised, as well as the home use of the BSI. c, Photographs showing the maximal hip flexion and associated flexor muscle activity before and after neurorehabilitation. d, Changes in lower limb motor scores over the course of both clinical trials. e, Plots reporting improvements in WISCI II scores over the course of both clinical trials. Neurorehabilitation supported by the BSI restored the capacity to walk over 10 m with crutches without any assistance or stimulation. f–h, Plots reporting quantifications of the 6 min walk test (f), weight-bearing capacity, time up and go, Berg Balance Scale (g) and observational gait analysis (h) (each dot refers to scores from a physiotherapist (n = 6, paired one-tailed t-test; **P = 0.002). N/A, not available.