Extended Data Fig. 5: Localization and function of autologous Treg cells after co-transplantation. | Nature

Extended Data Fig. 5: Localization and function of autologous Treg cells after co-transplantation.

From: Co-transplantation of autologous Treg cells in a cell therapy for Parkinson’s disease

Extended Data Fig. 5

a, b, After intra-striatal co-transplantation of Fischer 344 rats with TP medium and autologous Treg cells (20,000 cells per rat), (a) the localization of Treg cells was determined by immunofluorescence staining with anti-FOXP3 antibody at 1, 2, 3, 5 and 7 days after surgery. (One-way ANOVA, Tukey’s post-hoc test; n = 5 per group). b, The level of inflammatory cell infiltration into needle track was determined by immunohistochemical staining with anti-MHCII antibody. (Two-way ANOVA, Bonferroni’s multiple comparisons post-hoc test; n = 5 per group). Each error bar represents mean ± s.e.m. **P < 0.01, ***,P < 0.001.

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