Fig. 6: Comparison of a single-cell atlas between human and mouse limb.
From: A human embryonic limb cell atlas resolved in space and time
a, Overview of mouse sampling and the experimental scheme. The stars indicate timepoints. b, Overview of the analysis pipeline to integrate human and mouse scRNA-seq data. c, MultiMAP layout of integrated cells, coloured by integrated cell-type annotation or species (bottom right). Cluster abbreviations are the same as in Fig. 1. d, Broad cell-type proportions of each scRNA-seq library, with dissection region, ___location and species labelled at the bottom. NC, neural crest. e,f, Triangular diagrams (e) showing the cell-type proportion biases towards the proximal, middle or distal region of the human and mouse forelimb (left) and hindlimb (right), and a scatter plot (f) showing the fraction of hindlimb representation of each cell type. Each cell type or mean is represented by a circle (human) and a square (mouse), with size (square of diameter) denoting the average number of cells per segment (proximal, middle or distal).
