Fig. 2: Multi-tissue molecular endurance training responses.
From: Temporal dynamics of the multi-omic response to endurance exercise training
a, UpSet plot of the training-regulated gene sets associated with each tissue. Bars and dots indicating tissue-specific differential genes are coloured by tissue. Pathway enrichment analysis is shown for selected sets of genes in b,c as indicated by the arrows. b,c, Significantly enriched pathways (10% FDR) corresponding to genes that are differential in both LUNG and WAT-SC datasets (b) and the 22 genes that are training-regulated in all six tissues considered in a (c). Redundant pathways (those with an overlap of 80% or greater with an existing pathway) were removed. ESR, oestrogen receptor; TH17, T helper 17.
