Extended Data Fig. 8: Detection of triglyceride synthesized in microglia taken up by neurons through labelled 13C-glucose tracing.
From: APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia
a, Measurement of 13C-labelled triglycerides synthesized in microglia and profiled in neurons by lipidomics after exposure to microglia conditioned media. Microglia grown in uniformly labelled 13C-glucose (U-13C6-glucose) were challenged with fAβ or untreated. Each dot represents an individual replicate. n = 3 wells per condition; unpaired t-test; mean ± s.e.m.).
