Extended Data Fig. 1: Quality Control for single-nucleus RNA-sequencing data.
From: APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia
a, Doublet score distributions obtained with the Scrublet (0.2.3) Python package. Vertical lines indicate the doublet score thresholds identified per sample based on the distributions shown. b-e, Distribution of total read counts (b), number of genes expressed per cell (c), percent of reads mapped to ribosomal genes (d) and percent of reads mapped to mitochondrial genes (e) within the processed data after quality control. f, Percent of explained variance across the first 48 principal components.
