Extended Data Fig. 3: Attribution of signatures SBS40a, SBS40b, and SBS40c in a pan-cancer cohort.
From: Geographic variation of mutagenic exposures in kidney cancer genomes
Attribution of signatures SBS40a, SBS40b, and SBS40c in a pan-cancer cohort, showing a widespread distribution for SBS40a whilst SBS40b and SBS40c are only seen consistently in clear cell renal cell carcinomas (ccRCC). The size of each dot represents the proportion of samples of each tumor type where the signature is present. The color of each dot represents the average mutation burden.
