Extended Data Fig. 6: Transcription within the ecDNA interval of GBM39 cell lines.
From: Enhancing transcription–replication conflict targets ecDNA-positive cancers
(a) Read density of genomic assays in GBM39ec and GBM39HSR within the ecDNA interval in total counts per million (CPM). The mean of two biological replicates is shown for GRO-seq, Ribo-Zero and KAS-seq; a single replicate is shown for WGS. (b) Genome tracks highlighting the GBM39 ecDNA interval. One representative biological replication for each condition is visualized. (c) Genome tracks highlighting the increased transcription at EGFR-AS1 in GBM39ec compared to GBM39HSR. One representative biological replication for each condition is visualized.
