Extended Data Fig. 12: Correlative Light and Electron Microscopy (CLEM) of notoroids. | Nature

Extended Data Fig. 12: Correlative Light and Electron Microscopy (CLEM) of notoroids.

From: Timely TGFβ signalling inhibition induces notochord

Extended Data Fig. 12

a, Brightfield image of notoroid used to perform Correlative Light and Electron Microscopy (CLEM). b, Micro-CT and TNE-ZsGreen overview of notoroid; single z-planes of notoroid used in CLEM showing fluorescence of the TNE-ZsGreen reporter at the expected locations. c, Zoom of red box D in b) marking the beginning of the notochord population and the fibers associated with it shown as a maximum intensity projection of the SBF SEM data and a orthogonal reconstruction view below.

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