Extended Data Fig. 1: Single-cell RNA-seq of chick trunk development: HOX induction and markers of the neuromesodermal cell population.

a, Percentage of cells expressing different genes in the HOXB and HOXC clusters showing induction of HOXB/C9 between 7-10S. b, Embedding of chick trunk (4-13S) coloured by markers of endoderm and surface ectoderm. c, UMAP embedding detail plots highlighting the expression of several genes at and around the NMP cluster. Linear scale with maximum counts indicated by the squares.