Extended Data Fig. 10: The schematic diagram of IPHs-v1.0 for inbred lines. | Nature

Extended Data Fig. 10: The schematic diagram of IPHs-v1.0 for inbred lines.

From: Leveraging a phased pangenome for haplotype design of hybrid potato

Extended Data Fig. 10

a, The number of dSVs in the GON/STN group for inferring the ideal A inbred line. b, Similarly, the number of dSVs in the PHU group for designing the ideal E inbred line. c, Validating the power of recombination (simulated single recombination event) and haplotype selection in eliminating dSVs. We simulated selfing experiments and the distribution of dSVs in offspring. Two accessions (the optimal and worst-case scenarios) from heterotic group A, PG6359 and PG6029, are displayed. d, Similarly, two accessions (the optimal and worst-case scenarios) from heterotic group E, PG6245 and RH89-039-16. The simulated progenies show that recombination could dramatically reduce the number of dSVs at the haplotype level. e, Schematic diagram indicating the generation of ideal potato haplotypes (IPHs-v1.0) based on two heterotic groups including inbred lines E4-63 and A6-26. This approach prioritizes the minimization of the dSV count as its central objective. Recombination and haplotype selection could reduce the number of dSVs during potato recurrent selection.

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