Extended Data Fig. 4: Endogenous SIV Env-specific humoral responses in barcoded SIV challenge study animals.
From: Antibody prophylaxis may mask subclinical SIV infections in macaques
Longitudinal plasma antibody binding titers against SIVmac239 recombinant trimer measured as area under the curve (AUC) with pre-immune signal subtracted from 0 to 16 weeks post the dominant virus infection (as defined by the most abundant plasma virus barcode once sustained viremia occurred in each animal, see also supplementary Tables 1–3). (A) Each graph shows individual animal responses from groups 1–3 (from left to right, respectively). (B) Each group’s median antibody titer at each timepoint is shown with errors bars representing the IQR. Dotted lines equal 0. N = 4 (control group) or n = 6 (ITS102.03 and ITS103.1-treatment groups) animals.
